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Alcohol detoxification
Alcohol detoxification is a process by which a heavy drinker's system is brought back to normal after being used to having alcohol in the body on a continual basis. Serious alcohol addiction results in a decrease in production of GABA, a reuptake inhibitor, because alcohol acts to replace it. Precipitous withdrawal from long-term alcohol addiction without medical management can cause severe health problems and can be fatal. Alcohol detox is not a treatment for alcoholism. After detoxification, other treatments must be undergone to deal with the underlying addiction that caused the alcohol use.

Drug detoxification
Drug detoxification is used to reduce or relieve withdrawal symptoms while helping the addicted individual adjust to living without drug use; drug detoxification is not meant to treat addiction but rather an early step in long-term treatment. Detoxification may be achieved drug free or may use medications as an aspect of treatment. Often drug detoxification and treatment will occur in a community program that lasts several months and takes place in a residential rather than medical center.
Drug detoxification varies depending on the location of treatment, but most detox centers provide treatment to avoid the symptoms of physical withdrawal to alcohol & other drugs. Most also incorporate counseling and therapy during detox to help with the consequences of withdrawal.